Copanlisib dihydrochloride
Copanlisib dihydrochloride is a potent and selective pan-class I PI3K inhibitor with low nanomolar IC50 values. It demonstrates significant antitumor activity in preclinical models and exhibits high selectivity over other kinases. This compound is widely used in cancer research for investigating PI3K signaling in both cellular and animal studies.
Product Specifications
CAS Number
1402152-13-9
Product Name Alternative
Sub-nanomolar, phosphorylation, Phosphoinositide 3-kinase, PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, PI3K, Copanlisib Dihydrochloride, Copanlisib dihydrochloride, Copanlisib, antiproliferative, Apoptosis, antitumor, BAY 80-6946, BAY 80-6946 dihydrochloride, BAY 80-6946 Dihydrochloride, administration, AKT, Inhibitor, inhibit, mTOR, mTOP, intravenous
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.80% (May vary between batches)
Solubility
H2O:125 mg/mL (225.86 mM) ; DMSO:1 mg/mL (1.81 mM)
Smiles
Cl.Cl.COc1c (OCCCN2CCOCC2) ccc2C3=NCCN3C (NC (=O) c3cnc (N) nc3) =Nc12
Molecular Formula
C23H30Cl2N8O4
Molecular Weight
553.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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