Cyclopiazonic acid
Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite from Aspergillus flavus that acts as a potent nanomolar inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) . It is widely used in research to study calcium signaling, ER stress, and programmed cell death in both in vitro cellular models and in vivo plant studies.
Product Specifications
CAS Number
18172-33-3
Product Name Alternative
Cyclopiazonic acid, Calcium Channel, CalciumChannel, Ca2+ATPase, Ca channels, Ca2+ channels, inhibit, Inhibitor
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
>98%
Bioactivity
SR Ca2+ ATPase inhibitor
Form
Powder
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.89 mM) ; DMSO:100 mg/mL (297.28 mM)
Smiles
[H][C@@]12Cc3cccc4[nH]cc (c34) [C@]1 ([H]) [C@]1 ([H]) N (C (O) =C (C (C) =O) C1=O) C2 (C) C
Molecular Formula
C20H20N2O3
Molecular Weight
336.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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