Decoglurant
Decoglurant (RO4995819) is a negative allosteric modulator targeting metabotropic glutamate receptors 2 and 3 (mGluR2/3) . It has been investigated preclinically for its antidepressant potential, with studies exploring its effects in both in vitro receptor assays and in vivo behavioral models of depression.
Product Specifications
CAS Number
911115-16-7
Product Name Alternative
NAM, mGluR, mGluR2, mGluR3, Metabotropic glutamate receptors, inhibit, Inhibitor, Decoglurant, antidepressant, RO4995819, RO-4995819, RO 4995819
Field of Research
Neuroscience
Purity
99.39% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.18 mM) ; DMSO:230 mg/mL (514.15 mM)
Smiles
Nc1ccc (cn1) C#Cc1cnn2c (cc (nc12) -c1ccc (cc1) C (F) (F) F) C (F) (F) F
Molecular Formula
C21H11F6N5
Molecular Weight
447.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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