Delgocitinib
Delgocitinib (JTE-052) is a potent pan-JAK inhibitor with selectivity for JAK1, JAK2, JAK3, and Tyk2. It is a research tool for studying cytokine signaling in inflammatory and autoimmune disease models, where it has demonstrated efficacy in suppressing pruritus and inflammation in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
1263774-59-9
Product Name Alternative
TyrosineKinases, Tyrosine Kinases, Tyk2, Corectim, Corectim (Delgocitinib), Delgocitinib, Inhibitor, JAK, JAK1, JAK2, Janus kinase, JAK3, JTE052, JTE-052, JTE 052, inhibit
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.90% (May vary between batches)
Solubility
DMSO:240 mg/mL (773.32 mM)
Smiles
C[C@H]1CN (C (=O) CC#N) [C@]11CCN (C1) c1ncnc2[nH]ccc12
Molecular Formula
C16H18N6O
Molecular Weight
310.35
Storage Conditions
-20°C
Notes
For research use only.
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