Dynarrestin
Dynarrestin is a reversible aminothiazole inhibitor of cytoplasmic dynein 1 and 2. It blocks dynein 1-mediated microtubule motility in vitro and disrupts intracellular dynein-dependent transport without impairing ATPase activity or ciliogenesis. This tool compound is used to study dynein functions in processes like viral trafficking and organelle positioning in both cellular and biochemical assays.
Product Specifications
CAS Number
2222768-84-3
Product Name Alternative
LDC3
Field of Research
Neuroscience
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to at least 40 mg/ml)
Smiles
CCOC (=O) c1sc (Nc2ccc (F) cc2F) nc1-c1ccc (cc1) N (CC) CC
Molecular Formula
C22H23F2N3O2S
Molecular Weight
431.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
Ethyl 4- (4- (diethylamino) phenyl) -2- ((2,4-difluorophenyl) amino) thiozole-5-carboxylate
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