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Dynarrestin

Dynarrestin is a reversible aminothiazole inhibitor of cytoplasmic dynein 1 and 2. It blocks dynein 1-mediated microtubule motility in vitro and disrupts intracellular dynein-dependent transport without impairing ATPase activity or ciliogenesis. This tool compound is used to study dynein functions in processes like viral trafficking and organelle positioning in both cellular and biochemical assays.

Product Specifications

CAS Number

2222768-84-3

Product Name Alternative

LDC3

Field of Research

Neuroscience

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (up to at least 40 mg/ml)

Smiles

CCOC (=O) c1sc (Nc2ccc (F) cc2F) nc1-c1ccc (cc1) N (CC) CC

Molecular Formula

C22H23F2N3O2S

Molecular Weight

431.5

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

Ethyl 4- (4- (diethylamino) phenyl) -2- ((2,4-difluorophenyl) amino) thiozole-5-carboxylate

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