Thalidomide-O-amido-C4-N3
This compound is a cereblon E3 ligase ligand-linker conjugate based on a Thalidomide derivative. It serves as a key component in the construction of PROTACs for targeted protein degradation, a tool widely used in both in vitro and in vivo cancer and disease mechanism research.
Product Specifications
CAS Number
2098488-36-7
Product Name Alternative
Cereblon, Cereblon Ligand-Linker Conjugates 4, E3 Ligase Ligand-Linker Conjugates, E3 ligase Ligand-Linker Conjugates 18, LigandforE3Ligase, Ligand for E3 Ligase, inhibit, Inhibitor, Thalidomide O amido C4 N3, ThalidomideOamidoC4N3, Thalidomide-O-amido-C-4-N3, Thalidomide-O-amido-C4-N3
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
97.01% (May vary between batches)
Solubility
DMSO:40 mg/mL (93.37 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.67 mM)
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2OCC (NCCCCN=[N+]=[N-]) =O
Molecular Formula
C19H20N6O6
Molecular Weight
428.4
Storage Conditions
-20°C
Notes
For research use only.
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