MAK683
MAK683 is a potent and selective small molecule inhibitor of the Embryonic Ectoderm Development (EED) protein, with IC50 values ranging from 26 to 89 nM across multiple biochemical assays. This inhibitor is a valuable chemical probe for investigating the role of EED and PRC2 complex function in epigenetic regulation, cancer biology, and stem cell research, both in vitro and in vivo.
Product Specifications
CAS Number
1951408-58-4
Product Name Alternative
Inhibit, Inhibitor, MAK 683, MAK683, MAK-683, LC-MS, HistoneMethyltransferase, Histone Methyltransferase, ELISA, EED Alphascreen, EED
Field of Research
Epigenetics & Chromatin
Purity
98.16% (May vary between batches)
Solubility
DMSO:4.33 mg/mL (11.5 mM)
Smiles
Cc1ncccc1-c1cnc (NCc2c3CCOc3ccc2F) n2cnnc12
Molecular Formula
C20H17FN6O
Molecular Weight
376.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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