EML 425
EML 425 is a small molecule inhibitor that potently and selectively targets the CBP and p300 bromodomains, with respective IC50 values of 2.9 μM and 1.1 μM. This compound is a valuable chemical probe for epigenetic research, used in vitro to investigate the roles of these transcriptional coactivators in cancer and cellular differentiation pathways.
Product Specifications
CAS Number
1675821-32-5
Product Name Alternative
CBP, p300, inhibit, EML425, EML-425, EML 425, EpigeneticReaderDomain, Epigenetic Reader Domain, Inhibitor, Histone Acetyltransferase, HistoneAcetyltransferase, HATs, HAT
Field of Research
Epigenetics & Chromatin
Purity
97.60% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.35 mM) ; DMSO:250 mg/mL (567.55 mM)
Smiles
Cc1cc (O) cc (C) c1C=C1C (=O) N (Cc2ccccc2) C (=O) N (Cc2ccccc2) C1=O
Molecular Formula
C27H24N2O4
Molecular Weight
440.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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