Ritonavir
Ritonavir (ABT-538) is a peptidomimetic inhibitor of HIV-1 and HIV-2 proteases. While its own antiviral activity is limited by serum protein binding, it is widely used in research, both in vitro and in vivo, as a potent cytochrome P450 inhibitor to pharmacokinetically boost other protease inhibitors.
Product Specifications
CAS Number
155213-67-5
Product Name Alternative
ABT538, ABT-538, ABT 538, Abbott 84538, A 84538, A84538, A-84538, Apoptosis, HIVProtease, HIV Protease, HIV, Human immunodeficiency virus, Inhibitor, inhibit, Ritonavir, RTV, SARS-CoV, SARSCoV, SARS coronavirus
Field of Research
Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
>98%
Bioactivity
HIV1/2 protease inhibitor
Form
Powder
Solubility
Soluble in DMSO (12 mg/ml with warming) or in ethanol (5mg/ml)
Smiles
CC (C) [C@H] (NC (=O) N (C) CC1=CSC (=N1) C (C) C) C (=O) N[C@H] (C[C@H] (O) [C@H] (CC1=CC=CC=C1) NC (=O) OCC1=CN=CS1) CC1=CC=CC=C1
Molecular Formula
C37H48N6O5S2
Molecular Weight
720.9
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1,3-Thiazol-5-ylmethyl N-[ (2S,3S,5S) -3-hydroxy-5-[[ (2S) -3-methyl-2-[[methyl-2-[ (2-propan-2-yl-1,3-thiazol-4-yl) methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
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