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Selisistat R-enantiomer

EX-527 (R-enantiomer) is the less active enantiomer of the SIRT1 inhibitor Selisistat, exhibiting an IC50 > 100 μM against SIRT1. It serves as a critical negative control compound in biochemical and cellular research to validate the stereospecific activity of the active S-enantiomer in studies related to aging and neurodegenerative diseases.

Product Specifications

CAS Number

848193-69-1

Product Name Alternative

(R) -Selisistat, inhibit, Inhibitor, EX 527, EX527, EX-527, EX-527 (R-enantiomer), Selisistat R enantiomer, Selisistat Renantiomer, Selisistat R-enantiomer, SIRT1, Sirtuin

Field of Research

Epigenetics & Chromatin, Molecular Biology

Purity

99.78% (May vary between batches)

Solubility

DMSO:100 mg/mL (402.07 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (16.08 mM)

Smiles

NC (=O) [C@@H]1CCCc2c1[nH]c1ccc (Cl) cc21

Molecular Formula

C13H13ClN2O

Molecular Weight

248.71

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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