Selisistat R-enantiomer
EX-527 (R-enantiomer) is the less active enantiomer of the SIRT1 inhibitor Selisistat, exhibiting an IC50 > 100 μM against SIRT1. It serves as a critical negative control compound in biochemical and cellular research to validate the stereospecific activity of the active S-enantiomer in studies related to aging and neurodegenerative diseases.
Product Specifications
CAS Number
848193-69-1
Product Name Alternative
(R) -Selisistat, inhibit, Inhibitor, EX 527, EX527, EX-527, EX-527 (R-enantiomer), Selisistat R enantiomer, Selisistat Renantiomer, Selisistat R-enantiomer, SIRT1, Sirtuin
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
99.78% (May vary between batches)
Solubility
DMSO:100 mg/mL (402.07 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (16.08 mM)
Smiles
NC (=O) [C@@H]1CCCc2c1[nH]c1ccc (Cl) cc21
Molecular Formula
C13H13ClN2O
Molecular Weight
248.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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