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Foropafant

Foropafant (SR27417) is a potent and selective platelet-activating factor (PAF) receptor antagonist with a Ki of 57 pM. It effectively inhibits PAF-induced platelet aggregation in both rabbit and human systems, making it a valuable tool for studying PAF-mediated inflammation, anaphylaxis, and thrombosis in experimental research.

Product Specifications

CAS Number

136468-36-5

Product Name Alternative

Inhibit, Inhibitor, Foropafant, [3H]PAF binding, SR 27417, SR27417, SR-27417, Plateletaggregation, platelet-activating factor (PAF), Platelet aggregation

Field of Research

Pharmacology & Drug Discovery

Purity

99.13% (May vary between batches)

Solubility

DMSO:50 mg/mL (107.59 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.3 mM)

Smiles

CC (C) c1cc (C (C) C) c (-c2csc (n2) N (CCN (C) C) Cc2cccnc2) c (c1) C (C) C

Molecular Formula

C28H40N4S

Molecular Weight

464.71

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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