Foropafant
Foropafant (SR27417) is a potent and selective platelet-activating factor (PAF) receptor antagonist with a Ki of 57 pM. It effectively inhibits PAF-induced platelet aggregation in both rabbit and human systems, making it a valuable tool for studying PAF-mediated inflammation, anaphylaxis, and thrombosis in experimental research.
Product Specifications
CAS Number
136468-36-5
Product Name Alternative
Inhibit, Inhibitor, Foropafant, [3H]PAF binding, SR 27417, SR27417, SR-27417, Plateletaggregation, platelet-activating factor (PAF), Platelet aggregation
Field of Research
Pharmacology & Drug Discovery
Purity
99.13% (May vary between batches)
Solubility
DMSO:50 mg/mL (107.59 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.3 mM)
Smiles
CC (C) c1cc (C (C) C) c (-c2csc (n2) N (CCN (C) C) Cc2cccnc2) c (c1) C (C) C
Molecular Formula
C28H40N4S
Molecular Weight
464.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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