Gemcitabine elaidate hydrochloride
Gemcitabine elaidate hydrochloride (CP-4126) is a lipophilic, orally bioavailable prodrug of gemcitabine. It is activated intracellularly by esterases to release gemcitabine for phosphorylation, exhibiting schedule-dependent antitumor activity in preclinical in vivo and in vitro cancer models.
Product Specifications
CAS Number
2918768-08-6
Product Name Alternative
CP 4126 Hydrochloride, CP4126 Hydrochloride, CP-4126 Hydrochloride, CP-4126 hydrochloride, CO101 Hydrochloride, CO-101 Hydrochloride, CO-101 hydrochloride, CO 101 Hydrochloride, Gemcitabine elaidate hydrochloride, Gemcitabine elaidate hydrochloride (210829-30-4 (free base) ), Gemcitabine 5'-elaidate Hydrochloride, Gemcitabine 5'-elaidate hydrochloride, Gemcitabine elaidate Hydrochloride
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
98.50% (May vary between batches)
Solubility
DMSO:5.65 mg/mL (10.02 mM)
Smiles
O[C@@H] (C (F) (F) [C@H] (N1C (N=C (C=C1) N) =O) O2) [C@H]2COC (CCCCCCC/C=C/CCCCCCCC) =O.Cl
Molecular Formula
C27H44ClF2N3O5
Molecular Weight
564.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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