GNF179
GNF179 is an optimized 8,8-dimethyl isoprenoid analog demonstrating potent antimalarial activity against multidrug-resistant Plasmodium falciparum (W2 strain, IC50 = 4.8 nM) . It exhibits favorable in vitro metabolic stability and oral bioavailability in vivo, supporting its use as a chemical probe for parasitology and antimalarial drug discovery research.
Product Specifications
CAS Number
1261114-01-5
Product Name Alternative
GNF 179, GNF-179, GNF179, Inhibitor, Parasite, inhibit
Field of Research
Infectious Disease & Virology
Purity
97.80% (May vary between batches)
Solubility
DMSO:120 mg/mL (280.44 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.35 mM)
Smiles
CC1 (C) N (CCn2c (Nc3ccc (Cl) cc3) c (nc12) -c1ccc (F) cc1) C (=O) CN
Molecular Formula
C22H23ClFN5O
Molecular Weight
427.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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