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GSK-626616

GSK-626616 is a potent, orally bioavailable small molecule inhibitor of DYRK3 (IC50: 0.7 nM) with activity against other DYRK family kinases. It is a research tool for investigating DYRK family biology and has been explored in preclinical studies for potential therapeutic applications in conditions like anemia.

Product Specifications

CAS Number

1025821-33-3

Product Name Alternative

Dual specificity tyrosine regulated kinase, Dual specificity tyrosine phosphorylation regulated kinase, DYRK3, DYRK, Inhibitor, inhibit, GSK 626616, GSK626616, GSK-626616

Field of Research

Cell Biology, Signal Transduction

Purity

98.27% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.46 mM) ; DMSO:49 mg/mL (122.11 mM)

Smiles

Clc1cccc (Cl) c1NC1=NC (=O) \C (S1) =C\c1ccc2nccnc2c1

Molecular Formula

C18H10Cl2N4OS

Molecular Weight

401.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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