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Naftifine hydrochloride

Naftifine hydrochloride is a synthetic allylamine antifungal agent that acts by inhibiting squalene epoxidase, disrupting ergosterol biosynthesis and leading to squalene accumulation in fungal cells. It is used in research for studying antifungal mechanisms and has demonstrated efficacy in both in vitro assays and in vivo models of dermatophyte and yeast infections.

Product Specifications

CAS Number

65473-14-5

Product Name Alternative

Corporis, cruris, dermatophytes, Antibiotic, Exoderil, Fungal, Inhibitor, Hedgehog, Naftifine, Naftifine HCl, Naftifine Hydrochloride, Naftifine hydrochloride, Naftifungin, Naftin, inhibit, pedis, tinea, Smoothened

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Purity

98.75% (May vary between batches)

Solubility

DMSO:100 mg/mL (308.78 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.35 mM) ; H2O:2.5 mg/mL (7.72 mM) ; Ethanol:8 mg/mL (24.7 mM)

Smiles

Cl.CN (C\C=C\c1ccccc1) Cc1cccc2ccccc12

Molecular Formula

C21H22ClN

Molecular Weight

323.86

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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