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Trifluorothymidine

Trifluridine is a fluorinated thymidine analog with antineoplastic and antiviral properties. It functions by incorporating into DNA and inhibiting thymidylate synthase, thereby disrupting DNA synthesis and inducing apoptosis. This mechanism has been studied in vitro and in vivo for cancer research, particularly in models of colorectal carcinoma and herpesvirus infections.

Product Specifications

CAS Number

70-00-8

Product Name Alternative

α, α, α-Trifluorothymidine; Trifluorothymine deoxyriboside; Trifluridine; TFT

Field of Research

Cancer Biology, Molecular Biology

Purity

>98%

Bioactivity

Thymidylate synthase inhibitor; Anti cancer agent

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml) or in Water (up to 14 mg/ml)

Smiles

O=C1N ([C@@H]2O[C@H] (CO) [C@@H] (O) C2) C=C (C (F) (F) F) C (=O) N1

Molecular Formula

C10H11F3N2O5

Molecular Weight

296.20

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

2’-Deoxy-5-trifluoromethyluridine

Available Sizes

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