Trifluorothymidine
Trifluridine is a fluorinated thymidine analog with antineoplastic and antiviral properties. It functions by incorporating into DNA and inhibiting thymidylate synthase, thereby disrupting DNA synthesis and inducing apoptosis. This mechanism has been studied in vitro and in vivo for cancer research, particularly in models of colorectal carcinoma and herpesvirus infections.
Product Specifications
CAS Number
70-00-8
Product Name Alternative
α, α, α-Trifluorothymidine; Trifluorothymine deoxyriboside; Trifluridine; TFT
Field of Research
Cancer Biology, Molecular Biology
Purity
>98%
Bioactivity
Thymidylate synthase inhibitor; Anti cancer agent
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Water (up to 14 mg/ml)
Smiles
O=C1N ([C@@H]2O[C@H] (CO) [C@@H] (O) C2) C=C (C (F) (F) F) C (=O) N1
Molecular Formula
C10H11F3N2O5
Molecular Weight
296.20
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2’-Deoxy-5-trifluoromethyluridine
Available Sizes
Frequently Asked Questions
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