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Rimiducid

Rimiducid is a synthetic, lipid-permeable dimerizer based on a tacrolimus analog. It functions by cross-linking FKBP12 fusion proteins, such as inducible Caspase 9 suicide switches, to rapidly trigger apoptosis in engineered cells for controlled cell elimination in research applications, both in vitro and in vivo.

Product Specifications

CAS Number

195514-63-7

Product Name Alternative

Fatty Acid Synthase, FattyAcidSynthase, Fas, Fas receptor, FK506-binding protein, FKBP, Inhibitor, inhibit, AP 1903, AP1903, AP-1903, Apoptosis, Rimiducid

Field of Research

Cell Biology, Immunology & Inflammation, Metabolism Research

Purity

99.03% (May vary between batches)

Solubility

DMSO:135 mg/mL (95.63 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (1.77 mM)

Smiles

CC[C@H] (C (=O) N1CCCC[C@H]1C (=O) O[C@H] (CCc1ccc (OC) c (OC) c1) c1cccc (OCC (=O) NCCNC (=O) COc2cccc (c2) [C@@H] (CCc2ccc (OC) c (OC) c2) OC (=O) [C@@H]2CCCCN2C (=O) [C@@H] (CC) c2cc (OC) c (OC) c (OC) c2) c1) c1cc (OC) c (OC) c (OC) c1

Molecular Formula

C78H98N4O20

Molecular Weight

1411.63

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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