Rimiducid
Rimiducid is a synthetic, lipid-permeable dimerizer based on a tacrolimus analog. It functions by cross-linking FKBP12 fusion proteins, such as inducible Caspase 9 suicide switches, to rapidly trigger apoptosis in engineered cells for controlled cell elimination in research applications, both in vitro and in vivo.
Product Specifications
CAS Number
195514-63-7
Product Name Alternative
Fatty Acid Synthase, FattyAcidSynthase, Fas, Fas receptor, FK506-binding protein, FKBP, Inhibitor, inhibit, AP 1903, AP1903, AP-1903, Apoptosis, Rimiducid
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research
Purity
99.03% (May vary between batches)
Solubility
DMSO:135 mg/mL (95.63 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (1.77 mM)
Smiles
CC[C@H] (C (=O) N1CCCC[C@H]1C (=O) O[C@H] (CCc1ccc (OC) c (OC) c1) c1cccc (OCC (=O) NCCNC (=O) COc2cccc (c2) [C@@H] (CCc2ccc (OC) c (OC) c2) OC (=O) [C@@H]2CCCCN2C (=O) [C@@H] (CC) c2cc (OC) c (OC) c (OC) c2) c1) c1cc (OC) c (OC) c (OC) c1
Molecular Formula
C78H98N4O20
Molecular Weight
1411.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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