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AP20187

AP20187 is a cell-permeable, synthetic small molecule that induces dimerization of FKBP-fusion proteins. This tool is widely used in chemical biology for controlling protein localization, signal transduction, and gene expression in both cellular and animal models.

Product Specifications

CAS Number

195514-80-8

Product Name Alternative

AP 20187, AP20187, AP-20187, B/B Homodimerizer, FKBP homodimerizer, FKBP, FK506-binding protein, Inhibitor, inhibit

Field of Research

Cell Biology, Immunology & Inflammation

Purity

98.00% (May vary between batches)

Solubility

Ethanol:130 mg/mL (87.67 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.35 mM) ; DMSO:50 mg/mL (33.72 mM)

Smiles

CC[C@H] (C (=O) N1CCCC[C@H]1C (=O) O[C@H] (CCc1ccc (OC) c (OC) c1) c1cccc (OCC (=O) NCC (CNC (=O) COc2cccc (c2) [C@@H] (CCc2ccc (OC) c (OC) c2) OC (=O) [C@@H]2CCCCN2C (=O) [C@@H] (CC) c2cc (OC) c (OC) c (OC) c2) CN (C) C) c1) c1cc (OC) c (OC) c (OC) c1

Molecular Formula

C82H107N5O20

Molecular Weight

1482.75

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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