AP20187
AP20187 is a cell-permeable, synthetic small molecule that induces dimerization of FKBP-fusion proteins. This tool is widely used in chemical biology for controlling protein localization, signal transduction, and gene expression in both cellular and animal models.
Product Specifications
CAS Number
195514-80-8
Product Name Alternative
AP 20187, AP20187, AP-20187, B/B Homodimerizer, FKBP homodimerizer, FKBP, FK506-binding protein, Inhibitor, inhibit
Field of Research
Cell Biology, Immunology & Inflammation
Purity
98.00% (May vary between batches)
Solubility
Ethanol:130 mg/mL (87.67 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.35 mM) ; DMSO:50 mg/mL (33.72 mM)
Smiles
CC[C@H] (C (=O) N1CCCC[C@H]1C (=O) O[C@H] (CCc1ccc (OC) c (OC) c1) c1cccc (OCC (=O) NCC (CNC (=O) COc2cccc (c2) [C@@H] (CCc2ccc (OC) c (OC) c2) OC (=O) [C@@H]2CCCCN2C (=O) [C@@H] (CC) c2cc (OC) c (OC) c (OC) c2) CN (C) C) c1) c1cc (OC) c (OC) c (OC) c1
Molecular Formula
C82H107N5O20
Molecular Weight
1482.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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