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ARP-100

ARP-100 is a potent and selective MMP-2 inhibitor (IC50=12 nM) that binds the S1' pocket, demonstrating anti-invasive activity in Matrigel assays. It shows selectivity over MMP-1, -3, -7, and -9, making it a useful research tool for studying tumor invasion, metastasis, and angiogenesis in cancer models.

Product Specifications

CAS Number

704888-90-4

Product Name Alternative

Matrix metalloproteinases, matrix, matrigel, inhibit, Inhibitor, invasion, MMP-9, MMP-7, MMP-3, MMP-2 Inhibitor III, MMP-2, MMP-1, MMP, metalloproteinase, ARP 100, ARP100, ARP-100, anti-invasive, selective

Field of Research

Protein Biochemistry

Purity

97.18% (May vary between batches)

Solubility

DMSO:96 mg/mL (263.43 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.06 mM)

Smiles

CC (C) ON (CC (=O) NO) S (=O) (=O) c1ccc (cc1) -c1ccccc1

Molecular Formula

C17H20N2O5S

Molecular Weight

364.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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