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AS-1949490

AS1949490 is a potent and selective SHIP2 inhibitor (IC50=620 nM) that enhances glucose metabolism in L6 myotubes by upregulating GLUT1 expression. This compound is a valuable research tool for studying insulin signaling and metabolic disorders in cellular models.

Product Specifications

CAS Number

1203680-76-5

Product Name Alternative

SHP-2, Phosphatase, SHIP-2, Protein kinase B, PKB, diabetes, Akt, AS 1949490, AS1949490, AS-1949490, L6 myotubes, insulin signalling pathway, Inhibitor, glucose uptake, glucose consumption, inhibit

Field of Research

Cell Biology, Neuroscience

Purity

>98%

Bioactivity

SHIP2 inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to at least 40 mg/ml)

Smiles

C[C@H] (NC (=O) c1sccc1OCc1ccc (Cl) cc1) c1ccccc1

Molecular Formula

C20H18ClNO2S

Molecular Weight

371.9

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

3-[ (4-Chlorophenyl) methoxy]-N-[ (1S) -1-phenylethyl]-2-thiophenecarboxamide

Available Sizes

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