AS-1949490
AS1949490 is a potent and selective SHIP2 inhibitor (IC50=620 nM) that enhances glucose metabolism in L6 myotubes by upregulating GLUT1 expression. This compound is a valuable research tool for studying insulin signaling and metabolic disorders in cellular models.
Product Specifications
CAS Number
1203680-76-5
Product Name Alternative
SHP-2, Phosphatase, SHIP-2, Protein kinase B, PKB, diabetes, Akt, AS 1949490, AS1949490, AS-1949490, L6 myotubes, insulin signalling pathway, Inhibitor, glucose uptake, glucose consumption, inhibit
Field of Research
Cell Biology, Neuroscience
Purity
>98%
Bioactivity
SHIP2 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 40 mg/ml)
Smiles
C[C@H] (NC (=O) c1sccc1OCc1ccc (Cl) cc1) c1ccccc1
Molecular Formula
C20H18ClNO2S
Molecular Weight
371.9
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-[ (4-Chlorophenyl) methoxy]-N-[ (1S) -1-phenylethyl]-2-thiophenecarboxamide
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