Allitinib
Allitinib (AST-1306) is an irreversible, potent inhibitor of EGFR and ErbB2, exhibiting IC50 values of 0.5 nM and 3 nM, respectively. This small molecule is utilized in cancer research, demonstrating antitumor efficacy in both cellular assays and in vivo models of various carcinomas.
Product Specifications
CAS Number
897383-62-9
Product Name Alternative
HER1, Epidermal growth factor receptor, EGFRL858R/T790M, EGFR (T790M/L858R), EGFR, ErbB4, ErbB2, ErbB-1, Irreversible, inhibit, Inhibitor, ALS1306, ALS-1306, Allitinib, anti-cancer, ALS 1306, anilino-quinazoline, AST 1306, AST1306, AST-1306
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.10% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.46 mM) ; DMSO:55 mg/mL (122.53 mM)
Smiles
N (C=1C2=C (C=CC (NC (C=C) =O) =C2) N=CN1) C3=CC (Cl) =C (OCC4=CC (F) =CC=C4) C=C3
Molecular Formula
C24H18ClFN4O2
Molecular Weight
448.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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