ATN-224
ATN-224 (Bis (choline) tetrathiomolybdate) is an orally bioavailable, potent inhibitor of Cu/Zn-superoxide dismutase 1 (SOD1) . It exhibits dose-dependent inhibition of SOD1 activity in endothelial cells with an IC50 of 17.5±3.7 nM. This small molecule is utilized in research exploring oxidative stress mechanisms, angiogenesis, and in models of cancer and neurodegenerative diseases.
Product Specifications
CAS Number
649749-10-0
Product Name Alternative
SOD1, ATN 224, ATN224, ATN-224, Bis (choline) tetrathiomolybdate
Field of Research
Metabolism Research
Purity
99.45% (May vary between batches)
Solubility
DMSO:50 mg/mL (115.59 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.62 mM)
Smiles
S=[Mo] ([S-]) ([S-]) =S.OCC[N+] (C) (C) C.OCC[N+] (C) (C) C
Molecular Formula
C10H28MoN2O2S4
Molecular Weight
432.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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