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Auristatin F

Auristatin F is a potent microtubule-disrupting agent and vascular damaging compound. It serves as a highly effective cytotoxic payload in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy, with applications in both in vitro cytotoxicity assays and in vivo xenograft models.

Product Specifications

CAS Number

163768-50-1

Product Name Alternative

Conjugate, cytotoxin, damaging, ADC Cytotoxin, ADCCytotoxin, ADC Payload, agent, Auristatin F, inhibitor, inhibit, MicrotubuleAssociated, Microtubule/Tubulin, Microtubule Associated, microtubule, Microtubule, VDA, vascular

Field of Research

Signal Transduction

Purity

98.00% (May vary between batches)

Solubility

DMSO:195 mg/mL (261.4 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (6.7 mM)

Smiles

[C@H] ([C@H] (C (N[C@@H] (CC1=CC=CC=C1) C (O) =O) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@H] (C (C) C) N (C) C) =O) C (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]

Molecular Formula

C40H67N5O8

Molecular Weight

745.99

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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