Avoralstat
Avoralstat (BCX4161) is a small molecule plasma kallikrein inhibitor developed for hereditary angioedema. It is used in research to investigate the kallikrein-kinin pathway in both in vitro biochemical assays and in vivo preclinical models of angioedema.
Product Specifications
CAS Number
918407-35-9
Product Name Alternative
Threonine proteases, Serine proteases, Ser/Thr Protease, Serine endopeptidases, plasma kallikrein (PKK), Inhibitor, hereditary, oral, inhibit, bradykinin, BCX4161, BCX-4161, BCX 4161, Avoralstat, angioedema
Field of Research
Protein Biochemistry
Purity
95.12% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.89 mM) ; DMSO:50 mg/mL (97.36 mM)
Smiles
COc1cc (c (cc1C=C) C (=O) Nc1ccc (cc1) C (N) =N) -c1ccc (nc1C (O) =O) C (=O) NCC1CC1
Molecular Formula
C28H27N5O5
Molecular Weight
513.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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