AZD4320
AZD4320 is a dual BCL-2/BCL-xL inhibitor with reported IC50 values of 26 nM (KPUM-MS3), 17 nM (KPUM-UH1), and 170 nM (STR-428) in cellular assays. This small molecule is a research tool for studying apoptosis mechanisms and has been utilized in preclinical in vitro cancer models.
Product Specifications
CAS Number
1357576-48-7
Product Name Alternative
AZD4320, AZD-4320, AZD 4320, BCL-2, BCL2, Bcl-2 Family, BCLxL, BCL-xL, Inhibitor, inhibit
Field of Research
Cell Biology
Purity
98.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (5.29 mM) ; DMSO:125 mg/mL (132.2 mM)
Smiles
CN (CCO) CC[C@H] (CSc1ccccc1) Nc1ccc (cc1S (=O) (=O) C (F) (F) F) S (=O) (=O) NC (=O) c1ccc (cc1) N1CCC (CC1) [C@@H] (O) c1ccccc1-c1ccc (Cl) cc1
Molecular Formula
C45H48ClF3N4O7S3
Molecular Weight
945.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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