BAY-524
BAY-524 is a potent and selective small molecule inhibitor of the mitotic kinase Bub1, exhibiting an IC50 of 450 nM against the human enzyme with 2 mM ATP. This compound is a valuable research tool for studying chromosome segregation, spindle assembly checkpoint function, and mitotic progression in cellular and biochemical assays.
Product Specifications
CAS Number
1445830-39-6
Product Name Alternative
Recombinant catalytic domain, Shugoshin proteins (Sgo1and Sgo2), inhibit, Inhibitor, human Bub1, 2 mM ATP, anti-cancer, BAY 524, BAY524, BAY-524, BUB1 kinase, Bub1 kinase
Field of Research
Cell Biology, Metabolism Research
Purity
98.68% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.36 mM) ; DMSO:150 mg/mL (310.89 mM)
Smiles
CCOc1cc (F) c (Cn2nc (c (C) c2OC) -c2ncc (OC) c (Nc3ccncc3) n2) c (F) c1
Molecular Formula
C24H24F2N6O3
Molecular Weight
482.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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