Acemetacin
Acemetacin is a carboxymethyl ester prodrug of indomethacin, a potent NSAID derived from indol-3-acetic acid. It is primarily metabolized to its active form, offering improved gastric tolerability in clinical settings. This compound is utilized in pharmacological research to study inflammation and analgesia in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
53164-05-9
Product Name Alternative
Cyclooxygenase, COX, Acemetacin, Inhibitor, K708, K-708, K 708, inhibit, TVX 1322, TVX1322, TVX-1322
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Purity
99.26% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.81 mM) ; DMSO:77 mg/mL (185.18 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:54 mg/mL (129.86 mM)
Smiles
C (=O) (N1C=2C (C (CC (OCC (O) =O) =O) =C1C) =CC (OC) =CC2) C3=CC=C (Cl) C=C3
Molecular Formula
C21H18ClNO6
Molecular Weight
415.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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