BMX-IN-1
BMX-IN-1 is a potent and selective dual inhibitor of BMX and BTK kinases, with IC50 values of 8 nM and 10.4 nM, respectively. It demonstrates high selectivity, showing significantly reduced activity against Blk, JAK3, EGFR, Itk, and Tec. This inhibitor is a valuable chemical tool for studying TEC family kinase signaling in cancer and immunology research, both in vitro and in vivo.
Product Specifications
CAS Number
1431525-23-3
Product Name Alternative
Inhibit, Inhibitor, BMX IN 1, BMX Kinase, BMX kinase inhibitor, Bruton tyrosine kinase, Btk, BTK, BMXIN1, BMX-IN-1, BMX, Bmx
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
≥98% (May vary between batches)
Solubility
DMSO:8 mg/mL (15.25 mM) ; DMF:9 mg/mL (17.16 mM)
Smiles
Cc1ccc (cc1NC (=O) C=C) -n1c2c (ccc1=O) cnc1ccc (cc21) -c1ccc (NS (C) (=O) =O) cc1
Molecular Formula
C29H24N4O4S
Molecular Weight
524.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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