BOS-172722
BOS-172722 is a potent and selective small molecule inhibitor of the MPS1 kinase, demonstrating an IC50 of 2 nM. It is a valuable chemical probe for studying the spindle assembly checkpoint in cancer research, with utility in both in vitro biochemical assays and in vivo xenograft models to investigate mitotic arrest and aneuploidy.
Product Specifications
CAS Number
1578245-44-9
Product Name Alternative
Breast, autophosphorylation, cancer, BOS 172722, BOS172722, BOS-172722, inhibit, Inhibitor, Mps1, MPS1, Monopolar spindle 1
Field of Research
Signal Transduction
Purity
99.37% (May vary between batches)
Solubility
1M HCl:65 mg/mL (145.56 mM) ; DMSO:< 1.12 mg/mL
Smiles
CCOc1cc (ccc1Nc1ncc2cc (C) nc (NCC (C) (C) C) c2n1) -c1nncn1C
Molecular Formula
C24H30N8O
Molecular Weight
446.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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