Bragsin2
Bragsin2 is a cell-permeable, selective inhibitor of the BRAG2 GEF, blocking Arf GTPase activation with an IC50 of 3 μM. It functions by disrupting the BRAG2 PH domain-membrane interaction, preventing activation of lipidated Arf. This tool compound is used in cell-based studies to investigate Arf-dependent signaling pathways in cancer and neurology research.
Product Specifications
CAS Number
342795-08-8
Product Name Alternative
6-methoxy-5-nitro-2- (trifluoromethyl) chromen-4-one, Bragsin 2, Bragsin2, Bragsin-2, BRAG2, inhibit, Inhibitor
Field of Research
Cell Biology, Signal Transduction
Purity
98.47% (May vary between batches)
Solubility
DMSO:55 mg/mL (190.21 mM)
Smiles
COc1ccc2oc (cc (=O) c2c1[N+] ([O-]) =O) C (F) (F) F
Molecular Formula
C11H6F3NO5
Molecular Weight
289.16
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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