BRD6989
BRD6989 is a synthetic analog of cortistatin A that acts as a selective CDK8/19 kinase inhibitor, demonstrating an IC50 of approximately 200 nM. This compound is a valuable research tool for studying CDK8-mediated transcriptional regulation and has been utilized in both in vitro and in vivo models to investigate immunomodulation and oncology pathways.
Product Specifications
CAS Number
642008-81-9
Product Name Alternative
Cortistatin-A, CDK19/CycC, CDK19, CDK8/CycC, CDK8, BRD6989, BRD-6989, BRD 6989, CDK, Cyclin dependent kinase, BMDCs, Inhibitor, inhibit, ILReceptor, inflammatory, Interleukin, Interleukin Related, IL Receptor, IL-10, recombinant CDK19, recombinant CDK8
Field of Research
Cell Biology, Immunology & Inflammation
Purity
98.82% (May vary between batches)
Solubility
DMSO:11 mg/mL (41.61 mM) ;10% DMSO+90% Corn Oil:1 mg/mL (3.78 mM)
Smiles
CC1CCc2nc (N) c (C#N) c (-c3cccnc3) c2C1
Molecular Formula
C16H16N4
Molecular Weight
264.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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