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BRD-7389

BRD7389 is a potent small molecule inhibitor of the RSK kinase family, demonstrating IC50 values of 1.5 μM (RSK1), 2.4 μM (RSK2), and 1.2 μM (RSK3) . It is a valuable research tool for investigating RSK signaling in cancer cell proliferation and survival, with utility in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

376382-11-5

Product Name Alternative

Diabetes, DRAK1, CDK5/p35, colon, BRD7389, BRD-7389, BRD 7389, cancer, FLT3, Inhibitor, pancreatic, islets, inhibit, RSK, RSK2, RSK3, RSK1, S6 Kinase, S6K, S6Kinase, Ribosomal S6 Kinase (RSK), SNU-407, PIM1, Pim1, PKG1α, SGK

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction

Purity

>98%

Bioactivity

P90 RSK inhibitor; Increases insulin expression

Form

Powder

Solubility

Soluble in DMSO (up to 35 mg/ml) .

Smiles

O=C1c2ccccc2-c2c (NCCc3ccccc3) c (=O) [nH]c3cccc1c23

Molecular Formula

C24H18N2O2

Molecular Weight

366.42

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

1-[ (2-Phenylethyl) amino]-3H-naphtho[1,2,3-de]quinolone-2,7-dione

Available Sizes

Frequently Asked Questions

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