BRD-7389
BRD7389 is a potent small molecule inhibitor of the RSK kinase family, demonstrating IC50 values of 1.5 μM (RSK1), 2.4 μM (RSK2), and 1.2 μM (RSK3) . It is a valuable research tool for investigating RSK signaling in cancer cell proliferation and survival, with utility in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
376382-11-5
Product Name Alternative
Diabetes, DRAK1, CDK5/p35, colon, BRD7389, BRD-7389, BRD 7389, cancer, FLT3, Inhibitor, pancreatic, islets, inhibit, RSK, RSK2, RSK3, RSK1, S6 Kinase, S6K, S6Kinase, Ribosomal S6 Kinase (RSK), SNU-407, PIM1, Pim1, PKG1α, SGK
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction
Purity
>98%
Bioactivity
P90 RSK inhibitor; Increases insulin expression
Form
Powder
Solubility
Soluble in DMSO (up to 35 mg/ml) .
Smiles
O=C1c2ccccc2-c2c (NCCc3ccccc3) c (=O) [nH]c3cccc1c23
Molecular Formula
C24H18N2O2
Molecular Weight
366.42
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-[ (2-Phenylethyl) amino]-3H-naphtho[1,2,3-de]quinolone-2,7-dione
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