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Brilaroxazine

Brilaroxazine (RP5063) is a multimodal dopamine and serotonin modulator, acting as a partial agonist at D2, D3, D4, 5-HT1A, and 5-HT2A receptors and an antagonist at 5-HT2B and 5-HT7 receptors. Its pharmacological profile supports research into cognitive deficits associated with schizophrenia and Parkinson's disease, as evidenced in preclinical in vivo models.

Product Specifications

CAS Number

1239729-06-6

Product Name Alternative

Syndrome, ADHD, RP5063, RP-5063, RP 5063, Pulmonary, Serotonin Receptor, 5-HT7 Receptor, 5-HT7, 5HT Receptor, 5-hydroxytryptamine Receptor, 5HTReceptor, Alzheimer, 5-HT1A Receptor, 5-HT2B Receptor, 5-HT2A Receptor, 5-HT2B, 5-HT2A, 5-HT1A, 5-HT Receptor, autism, arterial, cardiac, DopamineReceptor, Dopamine Receptor, disorder, Tourette, depressive, D4 receptor, D4 Receptor, D2 receptor, D2 Receptor, D3 Receptor, D3 receptor, Brilaroxazine, Inhibitor, hypertension, inhibit, PAH, Parkinson

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

DMSO:95 mg/mL (210.94 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.33 mM)

Smiles

Clc1cccc (N2CCN (CCCCOc3ccc4OCC (=O) Nc4c3) CC2) c1Cl

Molecular Formula

C22H25Cl2N3O3

Molecular Weight

450.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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