BT2
BT2 is a potent and selective Mcl-1 inhibitor (Ki = 59 μM) and a BDK inhibitor (IC50 = 3.19 μM) . Its mechanism involves inducing conformational changes in BDK, leading to its dissociation from the BCKDC complex. This compound is a valuable research tool for studying apoptosis and branched-chain amino acid metabolism in cellular and biochemical assays.
Product Specifications
CAS Number
34576-94-8
Product Name Alternative
Inhibitor, Mcl-1, inhibit, Bcl-2 Family, BDK, BT-2, BT 2, BT2
Field of Research
Cell Biology
Purity
>98%
Bioactivity
BCKDC kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 20 mg/ml)
Smiles
OC (=O) c1sc2cc (Cl) ccc2c1Cl
Molecular Formula
C9H4Cl2O2S
Molecular Weight
247.10
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3,6-Dichlorobenzo[b]thiophene-2-carboxylic acid
Available Sizes
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