C 87
C 87 is a small molecule that directly inhibits TNF-α by binding to it, blocking TNF-α-induced cytotoxicity (IC50 = 8.73 μM) and downstream signaling. It is a useful research tool for studying TNF-α-mediated inflammatory and autoimmune pathways in both cellular and animal models.
Product Specifications
CAS Number
332420-90-3
Product Name Alternative
Inhibitor, inhibit, C 87, C87, C-87, TNF Receptor, TNFR, TNFα-induced cytotoxicity, TNF-α, Tumor Necrosis Factor Receptor
Field of Research
Cell Biology
Purity
≥98% (May vary between batches)
Solubility
DMSO:5.06 mg/mL (10.06 mM)
Smiles
[O-][N+] (=O) c1cc (N\N=C2\C (=O) N (N=C2c2ccccc2) c2nc (cs2) -c2ccccc2) ccc1Cl
Molecular Formula
C24H15ClN6O3S
Molecular Weight
502.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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