Carboxyamidotriazole Orotate
Carboxyamidotriazole Orotate (L-651582 Orotate) is the orotate salt of the signal transduction inhibitor CAI, providing enhanced oral bioavailability. This cytostatic agent inhibits non-voltage-operated calcium channels and their downstream pathways, demonstrating antitumor, antiangiogenic, and anti-inflammatory activities in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
187739-60-2
Product Name Alternative
L651582, L-651582, L-651582 Orotate, leukaemia, L 651582, Inhibitor, myelogenous, inhibit, Bcr/Abl, CAI, CAI Orotate, Ca channels, Ca2+ channels, Calcium Channel, CalciumChannel, cancer, Carboxyamidotriazole, Carboxyamidotriazole Orotate, chronic, ovarian, toxicity
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.37% (May vary between batches)
Solubility
DMSO:5 mg/mL (8.61 mM)
Smiles
OC (=O) c1cc (=O) [nH]c (=O) [nH]1.NC (=O) c1nnn (Cc2cc (Cl) c (C (=O) c3ccc (Cl) cc3) c (Cl) c2) c1N
Molecular Formula
C22H16Cl3N7O6
Molecular Weight
580.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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