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CCX140

CCX140-B is a selective CCR2 chemokine receptor antagonist. It has been utilized in research to investigate the role of CCR2 in inflammatory and metabolic diseases, including studies in animal models of diabetic nephropathy and atherosclerosis.

Product Specifications

CAS Number

1100318-47-5

Product Name Alternative

CCX 140, CCX140, CCX-140, CCX140-B, CCR5, CCR2, hCCR2

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Purity

97.58% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.07 mM) ; H2O:0.25 mg/mL (0.5 mM) ; DMSO:100 mg/mL (201.67 mM)

Smiles

Cc1cnc (C (=O) c2ncnc3[nH]ccc23) c (NS (=O) (=O) c2ccc (Cl) c (c2) C (F) (F) F) c1

Molecular Formula

C20H13ClF3N5O3S

Molecular Weight

495.86

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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