CDK9-IN-2
CDK9-IN-2 is a potent and selective CDK9 inhibitor, demonstrating IC50 values of 5 nM in A2058 melanoma cells and 7 nM in H929 multiple myeloma cells after 72-hour treatments. This compound is a valuable chemical probe for studying transcriptional regulation in oncology research, particularly in hematological and solid tumor models, both in vitro and in vivo.
Product Specifications
CAS Number
1263369-28-3
Product Name Alternative
Cyclin dependent kinase, CDK, CDK9 IN 2, CDK9, CDK9IN2, CDK-9-IN-2, CDK9-IN-2, inhibit, Inhibitor, H929 multiple myeloma cell line
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
99.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.7 mM) ; DMSO:70 mg/mL (164.35 mM)
Smiles
N[C@H]1CC[C@@H] (CC1) Nc1cc (c (Cl) cn1) -c1cccc (NCc2cccc (F) c2) n1
Molecular Formula
C23H25ClFN5
Molecular Weight
425.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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