CGP-37157
CGP37157 is a potent Na+/Ca2+ exchanger (NCX) inhibitor with an IC50 of 0.8 μM for blocking Na+-induced mitochondrial Ca2+ release in guinea pig hearts. This small molecule is a valuable research tool for studying calcium homeostasis and NCX function in cardiac physiology and pathophysiology, both in vitro and in vivo.
Product Specifications
CAS Number
75450-34-9
Product Name Alternative
CGP 37157, CGP37157, CGP-37157, 7-Chloro-5- (2-chlorophenyl) -1,5-dihydro-4,1-benzothiazepine-2 (3H) -one, Ca2+ Exchanger, Ca2+Exchanger, Inhibitor, inhibit, Na+ Exchanger, Na+/Ca2+ exchanger, Na+Exchanger, Na+/Ca2+ Exchanger
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Mitochondrial Na+/Ca2+ exchanger inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) .
Smiles
Clc1ccc2NC (=O) CSC (c3ccccc3Cl) c2c1
Molecular Formula
C15H11Cl2NOS
Molecular Weight
324.22
Storage Conditions
RT
Notes
For research use only.
Other Product Names
7-Chloro-5- (2-chlorophenyl) -1,5-dihydro-4,1-benzothiazepin-2 (3H) -one
Available Sizes
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