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CGP-37157

CGP37157 is a potent Na+/Ca2+ exchanger (NCX) inhibitor with an IC50 of 0.8 μM for blocking Na+-induced mitochondrial Ca2+ release in guinea pig hearts. This small molecule is a valuable research tool for studying calcium homeostasis and NCX function in cardiac physiology and pathophysiology, both in vitro and in vivo.

Product Specifications

CAS Number

75450-34-9

Product Name Alternative

CGP 37157, CGP37157, CGP-37157, 7-Chloro-5- (2-chlorophenyl) -1,5-dihydro-4,1-benzothiazepine-2 (3H) -one, Ca2+ Exchanger, Ca2+Exchanger, Inhibitor, inhibit, Na+ Exchanger, Na+/Ca2+ exchanger, Na+Exchanger, Na+/Ca2+ Exchanger

Field of Research

Neuroscience

Purity

>98%

Bioactivity

Mitochondrial Na+/Ca2+ exchanger inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml) .

Smiles

Clc1ccc2NC (=O) CSC (c3ccccc3Cl) c2c1

Molecular Formula

C15H11Cl2NOS

Molecular Weight

324.22

Storage Conditions

RT

Notes

For research use only.

Other Product Names

7-Chloro-5- (2-chlorophenyl) -1,5-dihydro-4,1-benzothiazepin-2 (3H) -one

Available Sizes

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