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CGS 15943

CGS 15943 is a potent, orally active non-xanthine adenosine receptor antagonist with high affinity for human A1 (Ki=3.5 nM) and A2A (Ki=4.2 nM) receptors. It is widely used as a pharmacological tool in vitro and in vivo to study adenosine signaling in research areas such as cardiovascular function, neuroprotection, and inflammation.

Product Specifications

CAS Number

104615-18-1

Product Name Alternative

Inhibit, p110δ, p110γ, P1 receptor, Inhibitor, CGS 15943, CGS15943, CGS-15943, AdenosineReceptor, adenosine A2B receptor, adenosine A3 receptor, adenosine A1 receptor, adenosine A2A receptor, Adenosine Receptor, A3, A2A, A2B, A1, Phosphoinositide 3-kinase, PI3K

Field of Research

Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Purity

97.40% (May vary between batches)

Solubility

DMSO:12.22 mg/mL (42.77 mM) ;10% DMSO+90% Corn Oil:1 mg/mL (3.5 mM)

Smiles

Nc1nc2ccc (Cl) cc2c2nc (nn12) -c1ccco1

Molecular Formula

C13H8ClN5O

Molecular Weight

285.69

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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