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VU-29

VU-29 is a potent and selective positive allosteric modulator of the mGlu5 receptor, exhibiting an EC50 of 9 nM. Its selectivity over other mGluR subtypes makes it a valuable research tool for investigating mGlu5 function in neuropharmacology, synaptic plasticity, and related in vitro and in vivo models.

Product Specifications

CAS Number

890764-36-0

Product Name Alternative

Allosteric, hippocampal, Inhibitor, inhibit, mGluR, Metabotropic glutamate receptors, LTD, LTP, rat, potentiator, VU29, VU-29, VU 29

Field of Research

Neuroscience

Purity

99.47% (May vary between batches)

Solubility

DMSO:25 mg/mL (65.04 mM)

Smiles

N (C (=O) C1=CC=C (N (=O) =O) C=C1) C=2N (N=C (C2) C3=CC=CC=C3) C4=CC=CC=C4

Molecular Formula

C22H16N4O3

Molecular Weight

384.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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