LY2874455
LY2874455 is a potent pan-FGFR inhibitor investigated in preclinical and clinical studies for advanced cancers. It has demonstrated activity in both in vitro cellular assays and in vivo tumor models targeting FGFR-driven malignancies.
Product Specifications
CAS Number
1254473-64-7
Product Name Alternative
Inhibitor, FGFR4, FGFR3, FGFR, FGFR1, FGFR2, Fibroblast growth factor receptor, LY 2874455, LY-2874455, LY2874455, inhibit, VEGFR2
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.22% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.43 mM) ; DMSO:82 mg/mL (184.56 mM) ; Ethanol:53 mg/mL (119.29 mM)
Smiles
C[C@@H] (Oc1ccc2[nH]nc (\C=C\c3cnn (CCO) c3) c2c1) c1c (Cl) cncc1Cl
Molecular Formula
C21H19Cl2N5O2
Molecular Weight
444.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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