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Edoxaban

Edoxaban (Lixiana, DU-176b) is a potent, selective, and orally active direct inhibitor of coagulation factor Xa (FXa), exhibiting over 10,000-fold selectivity versus related serine proteases. This small molecule anticoagulant is widely used in research for investigating thrombosis, stroke prevention, and its pharmacological effects in both in vitro enzymatic assays and in vivo disease models.

Product Specifications

CAS Number

480449-70-5

Product Name Alternative

Lixiana, Edoxaban, FactorXa, Factor Xa, Thrombin

Field of Research

Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

97.67% (May vary between batches)

Solubility

DMSO:2.74 mg/mL (5 mM)

Smiles

N (C (=O) C1=NC2=C (S1) CN (C) CC2) [C@H]3[C@@H] (NC (C (NC4=CC=C (Cl) C=N4) =O) =O) CC[C@H] (C (N (C) C) =O) C3

Molecular Formula

C24H30ClN7O4S

Molecular Weight

548.06

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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